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An all-too-common type of spreadsheet is what I call a spaghetti application. The term stems from the fact that the parts of the application are difficult to follow, much like a plate of spaghetti. Most of these spreadsheets begin life as a reasonably focused single-user application. But over time they are passed along to others who make their own modifications. As requirements change and employees come and go, new parts are added and others are ignored. Before too long, the original purpose of the workbook may have been forgotten. The result is a file that is used frequently, but no one really understands exactly how it all works. Everyone who s involved with it knows that the spaghetti application should be completely reworked. But because nobody really understands it, the situation tends to worsen over time. Spreadsheet consultants make a lot of money untangling such applications. I ve found that, in most cases, the most efficient solution is to redefine the user needs and build a new application from scratch.

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A 12 bit converter in the head of a CCD camera converts an analogue voltage signal into one of 4096 possible digital values for processing and display on a computer ADC circuits in a CCD camera are noted for their high processing rate and low noise 215, 269 Analogue-to-digital unit (ADU) In digital imaging, the numeric value assigned to represent the amplitude of a photon signal The conversion factor used in making the assignment for example, 10 photoelectrons/ADU is called the gain factor 263 Analyzer A linear polarizer used to analyze or determine the plane of vibration of an incident ray of polarized light 118 Angular aperture See Aperture angle Anisotropic In describing the optical properties of an object or propagation medium, having dissimilar properties in different directions 121 Annulus In phase contrast microscopy, the transparent ring at the front aperture of the condenser that provides illumination of the specimen.

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So a, S., McCarthy, M.B., et al. (2001) Functionalized silk-based biomaterials for bone formation. J. Biomed. Mater. Res. 54(1): 139 148. Soong, H.K., and Kenyon, K.R. (1984) Adverse reactions to virgin silk sutures in cataract surgery. Ophthalmology 91(5): 479 483. Spangrude, G.J., Heimfeld, S., et al. (1988) Puri cation and characterization of mouse hematopoietic stem cells. Science 241(4861): 58 62. van Luyn, M.J., van Wachem, P.B., et al. (1992) Relations between in vitro cytotoxicity and crosslinked dermal sheep collagens. J. Biomed. Mater. Res. 26(8): 1091 1110. van Wachem, P.B., Plantinga, J.A., et al. (2001) In vivo biocompatibility of carbodiimide-crosslinked collagen matrices: Effects of crosslink density, heparin immobilization, and bFGF loading. J. Biomed. Mater. Res. 55(3): 368 378. Vunjak-Novakovic, G. (2003) The fundamentals of tissue engineering: scaffolds and bioreactors. Novartis Found. Symp. 249: 34 46; discussion 46 51, 170 174, 239 241. Vunjak-Novakovic, G., Freed, L.E., et al. (1996) Effects of mixing on the composition and morphology of tissue-engineered cartilage. AIChE J. 42: 850 860. Vunjak-Novakovic, G., Martin, I., et al. (1999) Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J. Orthop. Res. 17(1): 130 138. Vunjak-Novakovic, G., Obradovic, B., et al. (1998) Dynamic cell seeding of polymer scaffolds for cartilage tissue engineering. Biotechnol. Prog. 14(2): 193 202. Wozney, J.M. (1989) Bone morphogenetic proteins. Prog. Growth Factor Res. 1(4): 267 280. Yamagiwa, H., Endo, N., et al. (2001) In vivo bone-forming capacity of human bone marrowderived stromal cells is stimulated by recombinant human bone morphogenetic protein-2. J. Bone Miner. Metab. 19(1): 20 28.

Gore, N, 186 Gore-Felton, C, 583 Gorely, T, 514, 728, 851, 854 Gorman, C, 469, 474, 482 Gorsuch, R, 38, 427, 572, 743, 845 Goss, F L, 570 Goss, J, 299, 394, 395 Gossard, D, 568, 569 Gotsch, K, 379 Gottfried, A E, 698 Gottfried, A W, 698 Gottlieb, E, 76 Gottman, J M, 650 Goudas, M, 8, 9, 10, 62, 65, 300, 415, 416, 417, 540, 547, 548 Gould, D, 10, 39, 43, 59, 125, 197, 265, 272, 288, 289, 290, 291, 292, 294, 295, 296, 297, 298, 408, 409, 410, 413, 414, 415, 416, 417, 429, 621, 622, 623, 624, 626, 629, 631, 632, 635, 636, 637, 695 Gould, E A, 481 Goulet, C, 167 Grabowski, J, 871 Gracely, E J, 588 Graff, J, 650 Grafton, S T.

To handle minor cash disbursements, a petty cash fund should be established. Initially, the fund should be established with sufficient cash to handle approximately one month s transactions. The responsibility for accountability and administration of the fund should be controlled by one person. The amount of cash placed into the fund is called the fund limit and is accounted for at least monthly. A receipt, invoice, voucher, or a memorandum explaining the purpose of each disbursement must support payments from the fund. The receipt, invoice, voucher, or memoranda should be noted as paid in such a manner as to preclude reuse. Accountability of the fund is summarized as follows: Fund limit Cash (coin and currency on hand) Receipts